Alireza Shams; Hossein Jorab Bafan; Mohammadreza Darabi; Fatemeh Haj Manochehri; Amir Haji Abbasi Zarrabi
Volume 22, Issue 2 , May and June 2015, , Pages 532-542
Abstract
Background: Osteoporosis, an erosive bone defect, is one of the major problems among adults over fifty which makes high expenses and many body psychotic and also causes lots of social side effects on people. Antioxidants and some minerals especially trace elements like zinc may be useful as treatment ...
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Background: Osteoporosis, an erosive bone defect, is one of the major problems among adults over fifty which makes high expenses and many body psychotic and also causes lots of social side effects on people. Antioxidants and some minerals especially trace elements like zinc may be useful as treatment for osteoporosis. This study was aimed at evaluating the effects of co-treatment of vitamin E and zinc on bone healing parameters.
Materials & Methods: 39 female Vistar rats with weight range of 180-200 gram were studied. 7 rats were selected as control group and others were ovariectomized and divided to 3 experimental groups: treated with Vit. E daily 200 IU / kg (n=9), treated with zinc daily 22 mg/ lit(n=8) , treated with Vit. E & Zinc(n=9) and finally 8 rat as sham group. After 1 month levels of Calcitonin, Estrogen, Progesterone, Zinc and Calcium in blood samples were measured and evaluated.
Results: Calcitonin levels in blood serum in groups treated with Zinc and Vit. E & Zinc were significant comparing to sham & control groups. Estrogen and Progesterone levels decreased in all experimental groups comparing to control group and occurred changes were significant but Calcium levels in these groups did not show any difference comparing to control and sham groups. Zinc level in serum of all treated groups was altered significantly comparing to control group, although some increased in sham group but not significant.
Conclusion: Our result showed using new treatment methods like Vit. E with zinc could prevent bone loss as the serum index measured changes in treatment of osteoporosis.
MR DARABI; M KESHVARI; M MOHSENI
Volume 12, Issue 3 , September and October 2005, , Pages 11-16
Abstract
Background and Purpose: There are various therapies for stress urinary incontinence (SUI) which include conservative, medical and surgical therapies, each with advantages and disadvantages. In this article, the results of simultaneous needle suspension and anterior colporrhaphy in patients with SUI who ...
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Background and Purpose: There are various therapies for stress urinary incontinence (SUI) which include conservative, medical and surgical therapies, each with advantages and disadvantages. In this article, the results of simultaneous needle suspension and anterior colporrhaphy in patients with SUI who had grade III and II cystocele in physical examination.
Methods and Materials: From 1380 to 1382 (2000-2003), 135 women with complaints of UI referred to Urology and Gynecology clinics. Of these, 72 patients suffered from SUI and 21 patients from mixed urinary incontinence with a predominance of SUI. Due to SUI severity, physical examination (cystocele grade II and III) and failure of conservative therapies, 58 patients underwent simultaneous anterior colporrhaphy and needle suspension.
Results: Peri- and postoperative mortality did not occur. In 13 cases (22.4%), foley catheter was removed two days after surgery but they were unable to void. In 11 cases, the problem was solved after catheterization for one week. In 2 cases, UI occurred and CIC was recommended; after two weeks CIC, they were able to urinate. In one case, sonography and cystoscopy were done due to dysuria resistant to medical treatment; cystoscope was used to extract the suture which had migrated to the bladder. 55 patients (94.9%) indicated improved symptoms one year after surgery. Perfect success (dryness) was observed in 47 patients (81%). Urinary residue, measured one month after surgery, was less than the normal upper limit in all cases.
Conclusion: Success rate of this study is higher than previous studies. Simultaneous needle suspension and anterior colporrhaphy is therefore recommend for patients with SUI and grade III and II cystocele due to the high success rate and low morbidity and mortality rate of the procedure.